Where technology meets medicine

Empowering patients,
transforming healthcare

Innovative telemedicine solutions, personalized care plans, and cutting-edge digital health tools — backed by peer-reviewed evidence from 60+ hospitals worldwide.

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Trilema in numbers

60+ Hospitals Across 4 countries
15,000+ Active Patients Under remote monitoring
40+ Diseases Covered Across 12 specialties
30+ Publications Peer-reviewed journals

Trusted by leading pharma & technology organisations

Telefónica
T-Systems
Laberit
SAP
Koa Health
Seidor
Dedalus
VITAR
Deloitte
HP Care Pack
Stella Technology
Amgen
Bayer
AstraZeneca
Janssen
Novartis
Novo Nordisk
Siemens Healthineers
Pfizer
AbbVie
Celgene
Biogen
Telefónica
T-Systems
Laberit
SAP
Koa Health
Seidor
Dedalus
VITAR
Deloitte
HP Care Pack
Stella Technology
Amgen
Bayer
AstraZeneca
Janssen
Novartis
Novo Nordisk
Siemens Healthineers
Pfizer
AbbVie
Celgene
Biogen

Two flagship solutions,
one mission

From continuous remote monitoring to immersive hospital navigation — Trilema delivers end-to-end digital health innovation.

Remote Patient Monitoring

SALMA RPM

A comprehensive digital health platform connecting patients and clinical teams through personalized care protocols, AI-powered alerts, and seamless medical device integrations.

  • 40+ disease protocols across 12 specialties
  • AI-powered alerts & risk monitoring
  • HL7 FHIR & SNOMED CT interoperability
Hospital Digital Twin

HVT Platform

Immersive 360° virtual hospital tours and AI-powered indoor navigation — reducing patient anxiety, improving wayfinding, and delivering measurable marketing ROI.

  • HOSPIGUIDE 3D Engine with SLAM navigation
  • Multilingual voice narration & sign language
  • ASD-adapted routes & full accessibility
Explore HVT Platform

Clinical outcomes that
speak for themselves

Implementation of SALMA generates measurable impact on provider cost structures and operational efficiency — validated through randomized controlled trials.

🚑

Reduction in Emergency Visits

Reduced avoidable acute episodes through early detection and personalized intervention protocols.

Published in peer-reviewed journals
📉

Reduction in Admissions & Readmissions

Improved post-discharge monitoring and continuity of care through remote patient engagement.

Published in peer-reviewed journals
⏱️

Reduction in Hospital Stay

Accelerated safe discharge supported by structured remote follow-up and teleconsultation.

Published in peer-reviewed journals

Covering the full spectrum
of chronic care

SALMA supports over 40 disease protocols across eight major therapeutic areas, with validated clinical pathways for each.

Pneumology Endocrine & Digestive Cardiology Pediatrics & Adolescence Oncology & Hematology Neurology Hospital Pharmacy Rheumatology Traumatology Dermatology Women's Health Digitalization

Pneumology

  • Sleep apnea
  • Asthma
  • COPD
  • Cystic fibrosis
  • Pulmonary hypertension
  • Smoking

Endocrine & Digestive

  • Diabetes Mellitus II
  • IBD – Ulcerative Colitis
  • IBD – Crohn's disease
  • Growth hormone

Cardiology

  • Heart failure
  • Heart attack (ACS)
  • Heart transplant
  • Auricular fibrillation

Pediatrics & Adolescence

  • Diabetes Mellitus I
  • Childhood asthma
  • Neonates / Premature
  • Childhood obesity
  • Eating disorders
  • Attention deficit disorders
  • Autism spectrum disorders

Oncology & Hematology

  • Anticoagulation
  • Haemophilia
  • Multiple myeloma
  • Myelodysplastic syndrome
  • Chronic myeloid leukaemia
  • Chronic lymphatic leukaemia
  • Colorectal cancer
  • Breast cancer
  • Lung cancer

Neurology

  • Epilepsy
  • Parkinson's disease
  • Multiple sclerosis
  • Amyotrophic lateral sclerosis
  • Restless leg syndrome

Hospital Pharmacy

  • Pluripathological patient
  • Oral antineoplastics

Rheumatology, Dermatology & Other

  • Rheumatoid arthritis
  • Juvenile idiopathic arthritis
  • Psoriasis arthritis
  • Dermatology – Psoriasis
  • Infectious diseases – HIV/HCV
  • Osteoporosis & hip fracture
  • Endometriosis
  • Deep venous thrombosis

Digitalization of Care Processes

  • Home hospitalization
  • Paediatric ICU
  • Post-surgical follow-up
  • Emergencies for nursing homes

Peer-reviewed evidence

Trilema's clinical outcomes are independently validated and published in leading international medical journals.

Randomized Controlled Trial

Clinical Cardiology

· October 2021

A randomized controlled clinical trial of cardiac telerehabilitation with a prolonged remote patient monitoring strategy after an acute coronary syndrome — demonstrating significant improvements in patient adherence and clinical outcomes.

Randomized Controlled Trial

Journal of Cardiovascular Development and Disease

· February 2023

Does an eHealth Intervention Reduce Complications and Healthcare Resources? The mHeart single-center RCT showed measurable reductions in hospital readmissions and emergency visits through structured remote monitoring.

Pilot Study

Transplantation and Cellular Therapy

· June 2023

Feasibility of a New Model of Care for Allogeneic Stem Cell Transplantation Recipients Facilitated by eHealth — the MY-Medula Pilot Study validating digital monitoring in high-complexity oncology patients.

Observational Study

Journal of Clinical Medicine

· September 2025

Extended telemonitored follow-up after acute coronary syndrome significantly reduces outpatient visits, improves lipid profiles (triglycerides, VLDL, non-HDL cholesterol), and delivers higher patient experience scores compared to standard care — across 75 consecutively monitored patients.

Trusted by leading hospitals and scientific societies

SEOMSEFHSECSVRASTCTMDPI

60+ hospitals

Let's build the future of
patient care together

Connect with the Trilema team to explore how SALMA RPM and our Digital Twin can work in your hospital or healthcare system.